虎嗅

Why is it still effective, even when we know it’s just a placebo?

原文:为何明知是安慰剂,它还有效?

Summary of Key Points

This article focuses on the concept of "non-blind placebo" – a treatment method where doctors explicitly inform patients that it is merely a sugar pill, yet they still prescribe it. It explores the counterintuitive effectiveness of this approach, the possible reasons behind it, and similar phenomena in areas beyond medicine, such as consumer behavior and politics. The article argues that although non-blind placebos may seem ineffective, they can provide relief for certain conditions, possibly due to the psychological notion that "doing something is better than doing nothing," the doctor's gesture of care, and the patient's hope. It also reflects a contemporary trend where, in a world saturated with false information, "honest symbolic care" can be particularly comforting.

1. Non-blind Placebos: Why Do Doctors Prescribe Something That’s Clearly Just a Sugar Pill?

Traditional placebos work by deceiving patients into believing they are effective (for example, claiming a sugar pill is a cold remedy). However, non-blind placebos are different: doctors openly tell patients that it is a sugar pill with no medicinal ingredients, but they suggest it might make them feel better. The American Medical Association allows this practice as long as the patient gives informed consent. In fact, studies have shown that 97% of doctors have used such methods at some point in their careers (for instance, prescribing antibiotics for viral infections, which are ineffective against viruses but act as placebos).

The uniqueness of non-blind placebos lies in their transparency: they do not treat patients like fools but involve them in the decision-making process by informing them that they are trying a particular approach.

2. Are Non-blind Placebos Really Effective? The Research Results Are Mixed

There is no consensus on the effectiveness of non-blind placebos:

  • Positive Evidence: A 2021 study in *Science Reports* found that they could be effective for conditions such as menopausal hot flashes, seasonal allergies, and depression. An early study from 1963 (with a small sample size) showed that most of 15 patients with neurological disorders experienced symptom improvement after taking the sugar pills, and some even wanted to continue taking them.
  • Negative Views: A paper in the same journal in 2023 argued that the existing evidence is of very low quality and does not yet support their efficacy as a universal cure.

In summary, non-blind placebos may be beneficial, but more reliable research is needed to confirm this.

3. How Can Something That’s Clearly Just a Sugar Pill Still Have a Therapeutic Effect?

The article offers several possible explanations for this phenomenon:

  • The "Doing Something Is Better Than Doing Nothing" Bias: In psychology, this is known as the "action bias." Even if you know the pill is ineffective, the act of taking it can make you feel like you are taking active steps towards recovery.
  • The Sense of Ritual and Care: A doctor spending 15 minutes listening to your symptoms can be therapeutic in itself, similar to how talking to someone when you’re upset can improve your mood.
  • The Power of Hope: Patients who have tried many treatments without success may try a sugar pill with little to lose, and this hope can trigger positive physiological responses.
  • Psychological Inertia: We are conditioned from a young age to believe that doctors’ prescriptions are effective. Even knowing it’s a sugar pill, our brains may still respond as if the medication is real, similar to how watching a horror movie makes your heart beat faster.

4. Non-blind Placebos Are Not Limited to Medicine: They Exist in Consumer Behavior and Politics

The concept of non-blind placebos is not unique to medicine; it appears in various aspects of life:

  • Consumer Behavior: For example, ads in supermarkets explicitly state that they are advertisements (e.g., "We are filming a commercial") or use honest claims (e.g., "Research shows people remember ads for young parties, so this is a pool party ad"). This honesty makes consumers feel more engaged with the product.
  • Politics: Politicians can gain support by appearing confident and caring about their constituents, even if their policies lack substance. Voters often seek a sense of being cared for, not necessarily concrete solutions.

5. In a World of False Information, Why Are Honest Placebos Particularly Comforting?

In a world filled with deception (AI pretending to be humans, marketing exaggerating products, politicians making empty promises), the honesty of non-blind placebos stands out. They do not deceive patients but provide a sense of respect and recognition, which can be particularly comforting.

The article concludes by saying: "In a cynical world, a sugar pill that claims to be nothing more than a sugar pill might be the sweetest thing there is." This suggests that what we really crave is not necessarily practical benefits but the feeling of being genuinely cared for. The popularity of non-blind placebos reflects our desire for authenticity and attention.

This article explores not just medical practices but also the psychological needs of contemporary society – our longing for truth and recognition. The rise of non-blind placebos reflects this desire for genuine connection and care.